Demetrios  Braddock, M.D., Ph.D.



Associate Professor of Pathology.


Department of Pathology
Yale University School of Medicine
Lauder Hall, Room 404a
310 Cedar Street
New Haven, CT., 06510

Office: 203-737-1278
Lab: 203-737-4277
Fax: 203-785-6899

email: demetrios.braddock@yale.edu


Training:
Education:
A.B. '88 (Chemistry), Ph.D. '94 (Biochemistry), '96 M.D. -- The University of Chicago
Training:
Anatomic Pathology '96-'00 -- National Cancer Institute, NIH, Laboratory of Pathology
Research Fellowship '00-'02 -- Clinical Investigator, NCI
Fellowship '03 -- Genitourinary Pathology, Johns Hopkins Hospitals

Expertise:
Hematopathology
Genitourinary Pathology
Structural biology

Research Interests:
Structural biology of protein complexes implicated in the pathogenesis of cancer
Genetic transcription

Professional Service:
Fellow, College of American Pathlogists
Member, The Pluto Society

Other Links:

Lab Web Page

Selected Publications:

Crichlow, G. V., Zhou, H., Yang, Y., Hsiao, H-H, Frederick, K. B., Debrosse, M., Yang, Y., Folta-Stogniew, E. J., Chung., H-J, Fan, C., De La Cruz, E. M., Levens, D.L., Lolis E., and Braddock, D.T. Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition. (2008) EMBO, 27 277-289

Saunders, L.P., Ouellette, A., Bandle, R., Chang, W.C., Zhou, H., Misra, R.N., De La Cruz, E. M. and Braddock, D.T. Small molecule inhibitors of Autotaxin inhibit melanoma cell migration and invasion Molecular Cancer Therapeutics (2008), 7, 3352-3362.

Braddock, D.T., Baber, J. L., Levens, D., and Clore, G. M., The Solution Structure of a Complex between the KH3 domain of hnRNP K and Single Stranded DNA. (2002) EMBO, 21 3476-3485

Braddock, D.T., Louis, J. M., Baber, J. L., Levens, D., and Clore, G. M., Solution Structure and Dynamics of a Specific Complex Between the KH3 and KH4 Domains of FBP and the Single Stranded Far Upstream Element of C-Myc. (2002) Nature, 415 1051-1056

Braddock,D.T., Cai, M., Baber, J. L., Huang, Y., and Clore, G. M., Rapid Identification of Medium to Large Scale Interdomain Motion in Modular Proteins using Dipolar Couplings. (2001) J. Am. Chem. Soc, 123 8634-8635







Search PubMed Database for Demetrios Braddock


This page was last modified on: 09/29/2009