Pei  Hui, M.D., Ph.D.



Associate Professor of Pathology and
Director, Clinical Molecular Diagnostics Laboratory.

Department of Pathology
Yale University School of Medicine
P.O. Box 208023
310 Cedar Street, BML-254B
New Haven, CT 06520-8023

Office: 203-785-6498
Lab: 203-785-4492
Fax: 203-785-7146

email: pei.hui@yale.edu


Training:
Memorial Sloan-Kettering Cancer Center (Oncologic Pathology Fellowship)
Yale-New Haven Hospital (Anatomic and Clinical Pathology Residency)
Yale University School of Medicine (Postdoctoral Fellow)
State University of New York at Buffalo (Ph.D.)
Peking University/Beijing Medical University (M.S.)
Xi'an JiaoTong University/Xi'an Medical University (M.D.)

Expertise:
Gynecological Surgical Pathology (American Board of Pathology - Anatomic and Clinical Pathology)
Molecular Diagnostics (American Board of Medical Genetics and American Board of Pathology - Molecular Genetic Pathology)

Research Interests:
Dr. Hui's academic interests primarily focus on clinical and biological aspects of human neoplasia. Using molecular and genetic approaches, he has active research collaborations with clinical oncologists and basic science investigators in exploring the pathogenesis of several fascinating gynecological tumors including Type II endometrial carcinomas and gestational trophoblastic diseases. As director of the Yale Pathology Molecular Diagnostics Laboratories, he explores molecular methods in facilitating routine histological evaluations of neoplastic processes including solid tumors, lymphomas and translocation specific sarcomas.

Professional Service:
Member, United States and Canadian Academy of Pathology
Associate Member, Yale Comprehensive Cancer Center
Member, Association of Molecular Pathology
Member, International Society of Gynecological Pathologists

Other Links:

USCAP
International Society of Gynecological Pathologists
Association of Molecular Pathology

Selected Publications:

Lipata F, Parkash V, Talmor M, Bell S, Chen S, Maric V, Hui P. Precise DNA genotyping diagnosis of hydatidiform mole. Obstet Gynecol. 2010 Apr;115(4):784-94. Xu M, Schwartz P, Rutherford T, Azodi M, Santin A, Silasi D, Martel M, Hui P. HER-2/neu receptor gene status in endometrial carcinomas: a tissue microarray study. Histopathology. 2010 Jan;56(2):269-73. Yan Z, Hui P. Minimal uterine serous carcinoma with extrauterine tumor of identical morphology: an immunohistochemical study of 13 cases. Appl Immunohistochem Mol Morphol. 2010 Jan;18(1):75-9.

Xu ML, Yang B, Carcangiu ML, Hui P. Epithelioid trophoblastic tumor: comparative genomic hybridization and diagnostic DNA genotyping. Mod Pathol. 2009 Feb;22(2):232-8.

Jorge D, Hui P. Lack of genetic association between exaggerated placental site reaction and placental site trophoblastic tumor. International Journal of Gynecological Pathology. 2008 Oct;27(4):562-7. Bifulco C, Jonhson C, Hao LM, Kermalli H, Bell S, Hui P. Genotypic Analysis of Hydatidiform Mole: An Accurate and Practical Method of Diagnosis. American Journal of Surgical Pathology. 2008;32(4):445-451. Dotto J, Mezzetti T, Hui P. Primary or secondary? Genotyping confirmation of an ovarian primary carcinoid tumor. Int J Gynecol Pathol. 2008 Jan;27(1):33-6.

Hui P, Wang HL, Chu PG, Yang B, Huang J, Baergen RN, Sklar J, Yang XY, Soslow RA. Absence of Y Chromosome in Human Placental Site Trophoblastic Tumor. Modern Pathology 2007;20(10):1055-60.

Fadare O, Parkash V, Carcangiu ML, Hui P. Epithelioid trophoblastic tumor: clinicopathological features with an emphasis on uterine cervical involvement. Modern Pathology. 2006; 19(1):75-82.

Hui P, Fedoriw G. Recurrent endometrial stromal tumors with smooth-muscle differentiation and a protracted clinical course. Nature Clinical Practice Oncololgy. 2005;2(11):588-593. Hui P, Martel M, Parkash V.Gestational Trophoblastic Diseases: Recent Advances in Histopathologic Diagnosis and Related Genetic Aspects. Adv Anat Pathol. 2005;12(3):116-125. Hui P, Kelly M, O'Malley DM, Tavassoli F, Schwartz PE. Minimal uterine serous carcinoma: a clinicopathological study of 40 cases. Modern Pathology. 2005;18(1):75-82.

Hui P, Riba A, Pejovic T, Johnson T, Baergen RN, Ward D. Comparative genomic hybridization study of placental site trophoblastic tumour: a report of four cases. Mod Pathol. 2004 Feb;17(2):248-51. Fadare O, Parkash V, Yilmaz Y, Mariappan MR, Ma L, Hileeto D, Qumsiyeh MB, Hui P. Perivascular epithelioid cell tumor (PEComa) of the uterine cervix associated with intraabdominal "PEComatosis": A clinicopathological study with comparative genomic hybridization analysis. World J Surg Oncol. 2004 Oct 19;2:35.

Hui P, Howe JG, Crouch J, Nimmakayalu M, Qumsiyeh MB, Tallini G, Flynn SD, Smith BR. Real-time quantitative RT-PCR of cyclin D1 mRNA in mantle cell lymphoma: comparison with FISH and immunohistochemistry. Leukemia Lymphoma. 2003 Aug;44(8):1385-94. Hui P, Glusac EJ, Sinard JH, Perkins AS. Clonal analysis of cutaneous fibrous histiocytoma (dermatofibroma). J Cutan Pathol. 2002 Aug;29(7):385-9. Zambrano E, Marshalko SJ, Jaffe CC, Hui P. Isolated noncompaction of the ventricular myocardium: clinical and molecular aspects of a rare cardiomyopathy. Lab Invest. 2002 Feb;82(2):117-22. Hui P, Perkins A, Glusac E. Assessment of clonality in melanocytic nevi. J Cutan Pathol. 2001 Mar;28(3):140-4. Hui P, Parkash V, Perkins AS, Carcangiu ML. Pathogenesis of placental site trophoblastic tumor may require the presence of a paternally derived X chromosome. Laboratory Investigation 2000;80(6):965-72.

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This page was last modified on: 05/19/2010