Gilbert W. Moeckel, M.D., Ph.D.



Associate Professor of Pathology and
Director of Renal Pathology and Electron Microscopy Laboratory.

Department of Pathology
Yale University School of Medicine
P.O.Box 208023
310 Cedar St., BML165
New Haven, CT 06520-8023

Office: 203-737-2803
Lab: 203-785-2750
Fax: 203-785-3348

email: gilbert.moeckel@yale.edu


Training:
Ludwig Maximillians University Munich: MD, PhD 1993
University of Arizona, Nephrology Division: Post Doctoral Fellowship, 1993-1996
University of Arizona: Anatomic and Clinical Pathology Residency, 1996-1999
University of Arizona: Renal Pathology Fellowship, 1999-2000

Academic Positions:

Assistant Professor of Pathology and Medicine, Department of Pathology, Renal Pathology Division, Vanderbilt University Medical Center: 2000-2008



Expertise:
Renal Pathology
Ultrastructural Pathology

Research Interests:
Hyperosmotic stress response and survival mechanisms in medullary kidney cells
Progression of fibrosis in CKD
Microenvironment of renal cell carcinoma: Role of COX2

Professional Service:
Medical Renal Biopsy Service; Electron Microscopy Service

Other Links:

Moeckel Lab

Selected Publications:

GW Moeckel, L Zhang, X Chen, M Rossini, R Zent and A Pozzi. Role of integrin alpha 1 beta 1 in the regulation of renal medullary osmolyte concentration. Am J Physiol, 2006, 290:F223-31.

Gilbert W. Moeckel, Li Zhang, Chuan-Ming Hao, Agnes B. Fogo, Ambra Pozzi and Matthew D. Breyer. COX2 activity promotes organic osmolyte accumulation adaptation of renal medullary interstitial cells from hypertonic stress. J Biol Chem 278(21):19352-19357, 2003.

Gilbert W. Moeckel, Kathy Jabs and Agnes B. Fogo. An 11-year-old African American girl with systemic lupus erythematosus and ANCA-negative renal vasculitis. Am J Kid Dis 39(2):433-438, 2002.

Gilbert W. Moeckel, Ramin Shadman, Joy M. Fogel and Sayed M.H. Sadrzadeh. Organic osmolytes betaine, sorbitol and inositol are potent inhibitors of erythrocyte membrane ATPases. Life Sciences 71(20):2413-2424, 2002.

Gilbert W. Moeckel and Yeong-Hau H. Lien. Distribution of de novo synthesized betaine in rat kidney: role of renal synthesis on medullary betaine accumulation. American Journal of Physiology 272(Renal Physiol. 41):F94-F99. 1997.

Gilbert W. Moeckel, Li-Wen Lai, Walter G. Guder, H. Moo Kwon and Yeong-Hau H. Lien. Kinetics and osmoregulation of Na and Cl-dependent betaine transporter in rat renal medulla. American Journal of Physiology 272(Renal Physiol. 41):F100-F106, 1997.

Gilbert W. Moeckel and Yeong Hau H. Lien. Bicarbonate dependency of betaine synthesis in cultured LLC PKI cells. American Journal of Physiology 266:F512-F515, 1994.

Gilbert W. Moeckel, Juergen Hallbach and Walter G. Guder. Purification of human and rat kidney aldose reductase. Enzyme Protein 48:45-50, 1994-95.

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This page was last modified on: 08/01/2009