YALE PATHOLOGY - Research Labs

Figure 2:
In vitro three-dimensional angiogenesis assay. Endothelial cells are placed in a collagen gel and form chords resembling blood vessels. Image shows cells stained with DAPI (blue nuclei), phalloidin (actin cytoskeleton). Green fluorescence is indicative of matrix metalloproteinase activity, which is required for angiogenesis.