Training: B.S.
Biochemistry, University
of Belgrade, YU. M.S. Microbiology
and Immunology, University of
Illinois at Chicago, IL.
Expertise: Experienced
in maintaining bacterial and
mammalian cell cultures, cloning,
immunofluorescence analysis, protein
purification , phage
display .
Research
Interests:Proteins
that interact with spectrin and
ankyrin and
their role in signal transduction and
vesicle trafficking.
Selected
Publications:
1:
Viswanathan
VK,
Koutsouris
A,
Lukic
S,
Pilkinton
M,
Simonovic
I,
Simonovic
M,
Hecht
G.
Comparative
analysis
of
EspF
from
enteropathogenic
and
enterohemorrhagic
Escherichia
coli
in
alteration
of
epithelial
barrier
function.
Infect
Immun.
2004
Jun;72(6):3218-27.
PMID:
15155623
[PubMed
- indexed
for
MEDLINE]
2:
Simonovic
I,
Arpin
M,
Koutsouris
A,
Falk-Krzesinski
HJ,
Hecht
G.
Enteropathogenic
Escherichia
coli
activates
ezrin,
which
participates
in
disruption
of
tight
junction
barrier
function.
Infect
Immun.
2001
Sep;69(9):5679-88.
PMID:
11500444
[PubMed
- indexed
for
MEDLINE]
3:
Simonovic
I,
Rosenberg
J,
Koutsouris
A,
Hecht
G.
Enteropathogenic
Escherichia
coli
dephosphorylates
and
dissociates
occludin
from
intestinal
epithelial
tight
junctions.
Cell
Microbiol.
2000
Aug;2(4):305-15.
PMID:
11207587
[PubMed
- indexed
for
MEDLINE]
4:
Simonovic
I,
Patston
PA.
The
native
metastable
fold
of
C1-inhibitor
is
stabilized
by
disulfide
bonds.
Biochim
Biophys
Acta.
2000
Aug
31;1481(1):97-102.
PMID:
11004579
[PubMed
- indexed
for
MEDLINE]
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