YALE PATHOLOGY - Research Labs

Figure 4
In vitro trans-splicing of JAZF1 and JJAZ1 pre-mRNAs. Treatment of human endometrial stromal cells with desferroximine (DFO) simulates hypoxia and stimulates trans-splicing in nuclear extracts of these cells (HESC). RF is RNA from Rhesus monkey fibroblasts. RT-PCR results on left; sequence analysis of products on right, showing Rhesus JAZF1 sequence joined to JJAZ1.